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261. Org. Lett. 2023, 25, 33, 6105–6109

date:2023-11-21

Photoredox Catalyzed [3 + 2]-Annulation Reaction of Pyridinium 1,4-Zwitterionic Thiolates with Alkenes: Synthesis of Dihydrothiophenes


Yong-Chun Luo*, Yang Wang#, Run Shi#, Xu-Gang Zhang, Huan-Huan Zhang and Peng-Fei Xu*


https://doi.org/10.1021/acs.orglett.3c02068





Pyridinium 1,4-zwitterionic thiolates are usually used to develop ionic annulation reactions. However, radical reactions were rare. We developed a photoredox catalyzed [3 + 2]-annulation reaction of pyridinium 1,4-zwitterionic thiolates with alkenes, disclosed the new reactivity of pyridinium 1,4-zwitterionic thiolate, and provided a new synthetic method for dihydrothiophene.